IgA nephropathy (IgAN, also known as Berger's disease) is a kidney disease,
which affects the glomerulus. Glomeruli are the tiny blood filters where urine
is made. IgA nephropathy is the commonest "glomerulonephritis" (inflammation of
the glomerulus) found in the developed countries of the world. IgA is short for
immunoglobulin A, an antibody which usually helps the body to fight infections
and toxins (poisons) encountered in the gut and the lungs. In IgA nephropathy,
IgA is deposited in the glomerulus and sometimes goes on to cause problems.
Although much research is trying to fnd out why, it is still not understood why
IgA is deposited in the kidneys and why it only sometimes goes on to cause
problems.
Most commonly there are no symptoms at all. The urine of patients with IgA
usually contains a small amount of blood, sometimes with protein. In most cases
this is such a small amount of blood that it can not be seen ("microscopic
haematuria") and it can only be detected by putting a special dipstick into the
urine.
In most cases this condition does not affect normal life. There is no
special diet that will make the disease go away or get worse.
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